5'-nucleotidase from Shewanella violacea

Enzyme Description

Extremophile
Yes "psychrophilic" and "piezophilic" organism
EC Number

Sequence

Length: 569 amino acids
MKNKLIKGLVATAVLAALAGCGSDNDDKDVVLPATCAEAGEACTIFTVLHTNDNHGRFFENKYGEYGMAARKTLIDQIRAEVEANGGETILLSGGDINTGVPESDLQDAVPDFIGMNLIGYDAMAVGNHEFDNPLDVVDMQRKLANFPMLAANIYDKVSGTRYFDPYKVFDVNGLRIAVVGLTTEDTAKIANPEFIGGLEFTDPQEELKKVIQDIKDADAADLIFATTHMGHYADAASGSNAPGDVALARAMTAGDLAAVIGGHSQNPVCMEGDAYDAEFTPGGECKPDVQNGTFIMQAHEWGKYVGQANFEYFNDELHLASYKLIPVNLKAKDADGVRQFIGEEITPDATVLEIMQQYQNAGQEELLEVIGTTDGKLEGERAVVRTQQTNLGRLIAEAQRTKVGADFAVMNSGGVRASIEAGEITYKDVLTVQPFGNSITKSTMTGAEITEYLNAVATVDIGETGSGAYPQLVGIKMDVDCEAKTVAINDINGKGYAVDASYSFTVPSFNAAGGDGYPVLTPVMTGYVDAEVMYTFIKDIGDILLADFAPVASDIQFLNSNSTLACQR
Kiko Fujimori et al. (2019) β€” Differences in biochemical properties of two 5'-nucleotidases from deep- and shallow-sea Shewanella species under various harsh conditions
Bioscience, Biotechnology, and Biochemistry  Β· doi:10.1080/09168451.2019.1578641 β†—  Β· Activity - Classical
24 measurements
Database ID
Sequence Annotation
Explicit - Provided
Protein Source
Purified, bacterium Shewanella violacea

Experimental Data (24 measurements)

24 measurements β€” page 1 of 2
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Ethanol 10% 100.0 22.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetone 30% 100.0 18.7 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetone 20% 100.0 19.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetone 10% 100.0 35.0 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetonitrile 30% 100.0 3.1 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetonitrile 20% 100.0 3.1 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Acetonitrile 10% 100.0 10.2 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Isopropanol 30% 100.0 4.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Isopropanol 20% 100.0 4.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Isopropanol 10% 100.0 30.9 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Ethanol 30% 100.0 2.7 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Ethanol 20% 100.0 3.7 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Glycerol 10% 100.0 84.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Methanol 30% 100.0 5.1 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Methanol 20% 100.0 7.8 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Methanol 10% 100.0 37.4 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Dimethylformamide (DMF) 30% 100.0 11.6 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Dimethylformamide (DMF) 20% 100.0 15.3 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Dimethylformamide (DMF) 10% 100.0 40.8 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
Activity - Classical Activity measured by colorimetric assay (Fiske-Subbarow method, absorbance measurement of the reduced reaction product of inorganic phosphate with ammonium molybdate, 740 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 30% 100.0 13.9 % 20 mM Tris-HCl buffer 8 30Β°C 4 mM ATP (Adenosine triphosphate) Adenosine 5β€²-diphosphate , inorganic phosphate 10 mM MgClβ‚‚ β€” Classical aqueous control (in %)
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Visualization : Activity β€” Classical

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Structure

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