Lipase from Bacillus sphaericus 205y

Enzyme Description

Extremophile
No
EC Number

Sequence

Length: 397 amino acids
MNQITNWRPRGFLQWLLTILSVIVCFIIIIVAYYIFNPSNMDKIMSLLAWGTSIFPIMLVVTAFIIIVLLALSFWKKTFIALTVLFPILLLLMFLTVQPISTMKSYAKSENVSVALSSHFFYNQNISTKPSVDVVYGKTTDGIELKLDVWPAKKKSEDVLTPVIVQVHGGGWVSGDKGQVQDWNQWMNDQGYTVFDVQYRMPPVAGWKDEVGDVKSAIGWIVQHADTYKIDPNRIILMGESAGGNLAMLAAYSLGDKHLPPSTDVPDVPIKAVINMYGPSDMTAFYKNNPSKRYVQDVLDQYIGGSPSDYPARYKKLSPISYIQEHTPPTIMFLGTGDRIVPVEQANVLDDKLTTSGVAHELYLLPKVDHGFDANPGSLSTQFAKEKVKAFLQKYNK
R. N. Z. A. Rahman et al. (2003) β€” Cloning and expression of a novel lipase gene from Bacillus sphaericus 205y
Molecular Genetics and Genomics  Β· doi:10.1007/s00438-003-0831-5 β†—  Β· Stability - Incubation
5 measurements
Database ID
UniProt: Q8VQP2 β†—
Sequence Annotation
Explicit - Provided
Protein Source
Recombinant, host bacterium Escherichia coli BL21

Experimental Data (5 measurements)

5 measurements
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Stability - Incubation Activity after incubation (30 minutes at 37Β°C) measured by absorbance spectrophotometry (colorimetric Kwon-Rhee assay, absorbance measurement of the free fatty acid reacting with cupric acetate–pyridine reagent product, 715 nm) in aqueous phase Dimethyl Sulfoxide (DMSO) 25% 100 10 % Incubation: Crude enzyme, Assay: Crude enzyme (1ml), Olive oil emulsion (2.5ml), 0.01 M calcium chloride ? Incubation: 37Β°C, Assay: 37Β°C ? mM Olive oil free fatty acids , glycerol β€” Incubation: 200 rpm, Assay: 200 rpm Water-incubated control (in %), assay in aqueous phase
Stability - Incubation Activity after incubation (30 minutes at 37Β°C) measured by absorbance spectrophotometry (colorimetric Kwon-Rhee assay, absorbance measurement of the free fatty acid reacting with cupric acetate–pyridine reagent product, 715 nm) in aqueous phase Acetonitrile 25% 100 0 % Incubation: Crude enzyme, Assay: Crude enzyme (1ml), Olive oil emulsion (2.5ml), 0.01 M calcium chloride ? Incubation: 37Β°C, Assay: 37Β°C ? mM Olive oil free fatty acids , glycerol β€” Incubation: 200 rpm, Assay: 200 rpm Water-incubated control (in %), assay in aqueous phase
Stability - Incubation Activity after incubation (30 minutes at 37Β°C) measured by absorbance spectrophotometry (colorimetric Kwon-Rhee assay, absorbance measurement of the free fatty acid reacting with cupric acetate–pyridine reagent product, 715 nm) in aqueous phase p-Xylene 25% 100 90 % Incubation: Crude enzyme, Assay: Crude enzyme (1ml), Olive oil emulsion (2.5ml), 0.01 M calcium chloride ? Incubation: 37Β°C, Assay: 37Β°C ? mM Olive oil free fatty acids , glycerol β€” Incubation: 200 rpm, Assay: 200 rpm Water-incubated control (in %), assay in aqueous phase
Stability - Incubation Activity after incubation (30 minutes at 37Β°C) measured by absorbance spectrophotometry (colorimetric Kwon-Rhee assay, absorbance measurement of the free fatty acid reacting with cupric acetate–pyridine reagent product, 715 nm) in aqueous phase n-Hexane 25% 100 110 % Incubation: Crude enzyme, Assay: Crude enzyme (1ml), Olive oil emulsion (2.5ml), 0.01 M calcium chloride ? Incubation: 37Β°C, Assay: 37Β°C ? mM Olive oil free fatty acids , glycerol β€” Incubation: 200 rpm, Assay: 200 rpm Water-incubated control (in %), assay in aqueous phase
Stability - Incubation Activity after incubation (30 minutes at 37Β°C) measured by absorbance spectrophotometry (colorimetric Kwon-Rhee assay, absorbance measurement of the free fatty acid reacting with cupric acetate–pyridine reagent product, 715 nm) in aqueous phase n-Hexadecane 25% 100 0 % Incubation: Crude enzyme, Assay: Crude enzyme (1ml), Olive oil emulsion (2.5ml), 0.01 M calcium chloride ? Incubation: 37Β°C, Assay: 37Β°C ? mM Olive oil free fatty acids , glycerol β€” Incubation: 200 rpm, Assay: 200 rpm Water-incubated control (in %), assay in aqueous phase

Visualization : Stability β€” Incubation

R. N. Z. A. Rahman et al. (2003)

One bar per measurement. Colour = solvent, shade = solvent volume.

Moohamad Ropaning Sulong et al. (2006) β€” A novel organic solvent tolerant lipase from Bacillus sphaericus 205y: Extracellular expression of a novel OST-lipase gene
Protein Expression and Purification  Β· doi:10.1016/j.pep.2006.04.015 β†—  Β· Stability - Incubation
11 measurements

Structure

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