Lipase (gene LipI.3_KE38) from Pseudomonas fluorescence KE38

Enzyme Description

Extremophile
Yes "psychro-tolerant" organism, "cold-active" enzyme
EC Number

Sequence

Length: 617 amino acids
MGVYDYKNFSTADSKALFTDAMAITLYSYHNLDNGFATGYQHNGLGLGLPATLVTALLGGTNSQGVIPGIPWNPDSEKAALDAVQKAGWTPITASQLGYDGKVDAHGTFFGEKAGYNTAQVEILGKYDAQGHLTEIGIAFRGTSGPRETLIGDSIGDVINDLLAALGPKDYAKNYVGEAFGNLLGDVVAFAQANGLSGKDVLVSGHSLGGLAVNSLADLSTDTWGGFFKDSNYIAYASPTQSATDNVLNVGYENDPVFRALDGSSFNLSSVGVHDAPKESATDNIVSFNDHYASTAWNVLPYSILNIPTWISHLPTAYGDGMNRVIESKYYDLTSKDSTIVVANLSDPARANTWVQDLNRNAETYKGSTFIIGSDANDLIQGGNGNDYLEGRDGNDTFRDGGGYSILLGGKGNNVLDLQQSVKAVEFAHDGAGTLYLRDANGGISITRDIGSIVSKEPGFLWGLFKDDVTHSVTANGLAVGNHLTAYASSVKGGGGADTLKAQATGDWLFGLDGNDHLIGGKGNDVFVGGAGNDVMESGGGVDTFLFSGSFGQDRVVGYQANDKLVFLGVQGVVANDDFRAHATAVGHDTVLTFGGDSVTLVGVGLDSLAGTGIVIA
Fulya Karakaş et al. (2020) β€” Gene cloning, heterologous expression, and partial characterization of a novel cold-adapted subfamily I.3 lipase from Pseudomonas fluorescence KE38
Scientific Reports  Β· doi:10.1038/s41598-020-79199-w β†—  Β· Activity - Classical
7 measurements
Database ID
Sequence Annotation
Explicit - Provided GenBank Accession Number
Protein Source
Recombinant, host bacterium Escherichia coli BL21 (DE3)

Experimental Data (7 measurements)

7 measurements
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Acetone 30% 100 90 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Acetonitrile 30% 100 135 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Methanol 30% 100 100 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Ethanol 30% 100 125 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Isopropanol 30% 100 10 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent n-Hexane 30% 100 65 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)
Activity - Classical Activity measured by titration (pH-stat) in the presence of organic solvent Ethyl Acetate 30% 100 30 % 50 mM Tris-HCl buffer incubation 8.5 25Β°C 5% Olive oil free fatty acids , glycerol β€” β€” Classical aqueous control (in %)

Visualization : Activity β€” Classical

One bar per measurement. Colour = solvent, shade = solvent volume.

Structure

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