Sucrose phosphorylase from Thermobacillus sp. ZCTH02-B1

Enzyme Description

Extremophile
Yes "thermophilic" organism
EC Number

Sequence

Length: 488 amino acids
MKLENRVQLITYPDSLGGNLAALREVLRRHFPGLFLGGIHILPPFPSSGDRGFAPLDYGMIDPAFGTWEDIAQLGEEYGVMLDVMVNHISRRSPQFMDFLKQGRSSPYADMFLTLDKIWPDGRPVQADIDKMFLRRKLPYSAFTVGDGREELVWTTFGKTDPSEQIDLDVRSPLARHYLSGIFQRFKANRVNMVRLDAVGYVIKKPGTSCFFVEPDIYEFLDWVADQAKEHDIALLPEVHAHYSIQYKLAERGFWIYDFILPFMVLDALVNRSSAMLLRYLRTRPANQFTMLDCHDGIPVKPDLDDLVDTAQARRVVDLCLARGANLSYVISDRHKSPDGFDVHQIRCTYYDALGRNDDAYLAARAIQLFVPGIPQIYYVGLLAGENDPARAEATGDGREINRHNYTLEEIEQAVRRPVVQRLLKLIRFRNEHEAFQGSFRVCESEDSKIRLEWEKDAIRCALHVDLDTYRSIITCTDGQGKEAQWVV
Yan Li et al. (2019) β€” Characterisation of a Thermobacillus sucrose phosphorylase and its utility in enzymatic synthesis of 2-O-Ξ±-d-glucopyranosyl-l- ascorbic acid
Journal of Biotechnology  Β· doi:10.1016/j.jbiotec.2019.08.018 β†—  Β· Activity - Classical
7 measurements
Database ID
Sequence Annotation
Explicit - Provided
Protein Source
Recombinant, host bacterium Escherichia coli BL21 (DE3)

Experimental Data (7 measurements)

7 measurements
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 20% 100 136 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 30% 100 132 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 35% 100 125 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 40% 100 121 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 45% 100 71 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 50% 100 39 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction
Activity - Classical Activity measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 55% 100 9 % 50 mM sodium phosphate buffer 7 55Β°C 150 mM Sucrose fructose , Glucose β€” β€” Classical aqueous control (in %) | EC number given for hydrolysis reaction, 2.4.1.7 for the EC number corresponding to the transferase reaction

Visualization : Activity β€” Classical

One bar per measurement. Colour = solvent, shade = solvent volume.

Structure

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