Endoglucanase EGtf2 from Thermobifida fusca

Enzyme Description

Extremophile
Yes "thermophilic" organism
EC Number

Sequence

Length: 616 amino acids
MTPLTRRLRAGAAAIAIGASALIPLTSSPAAASGTADWLHTDGNRIVDSAGNEVWLTGANWFGFNTSERMFHGLWAANIEDITSAMAERGINMVRVPISTQLLLEWKNGQAGPSGVNEYVNPELAGMNTLEVFDYWLQLCEEYGLKVMLDVHSAEADNSGHYYPVWYKGDITTEDFYTAWEWVTERYKNNDTIVAADIKNEPHGKANETPRAKWDGSTDIDNFKHVCETAGKRILAINPNMLILCEGIEIYPKDGQDWSSTDGRDYYSTWWGGNLRGVADHPVDLGAHQDQLVYSPHDYGPSVFEQPWFEGEWNRQTLTEDVWRPNWLYIHEDDIAPLLIGEWGGFLDGGDNEKWMTALRSLIIDEKMHHTFWALNPNSGDTGGLLNYDWTTWDEAKYAFLKPALWQDANGKFVGLDHDVPLGGVGSTTGVSLNQYYGGGGPSQPPTEPTEPPTEPTEPPTEPTEPPANPTGALEVYYRNNSLAADDSQIAPGLRLVNTGSSTVDLADVEIHYYFTNEPGGTLQFTCDWAQVGCANVNASFTSLSAPGADTSLVLTLSGSLAPGASTELQGRIHTANWANFDESDDYSRGTNTDWELSEVITAYLGGTLVWGTPPA
Li-Huan Qiu et al. (2011) β€” Thermostable Bacterial Endoglucanases Mined from Swiss-Prot Database
Applied Biochemistry and Biotechnology  Β· doi:10.1007/s12010-011-9368-y β†—  Β· Activity + Stability - Incubation
11 measurements
Database ID
UniProt: Q7X2N2 β†—
Sequence Annotation
Inferred - from protein name
Protein Source
Recombinant, host bacterium Escherichia coli BL21 (DE3)

Experimental Data (11 measurements)

11 measurements
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Methanol 50% 100 53 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Ethanol 50% 100 56 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Isopropanol 50% 100 73 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Acetone 50% 100 64 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 50% 100 59 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Dimethylformamide (DMF) 50% 100 25 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent Tetrahydrofuran (THF) 50% 100 4 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent 1-Propanol 50% 100 43 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent 1-Hexanol 50% 100 73 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent 1-Octanol 50% 100 146 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type
Activity + Stability - Incubation Activity after incubation (20 minutes at 50Β°C), measured by absorbance spectrophotometry (DNS assay, 540 nm) in the presence of organic solvent 1-Dodecanol 50% 100 270 % Incubation: 50 mM citrate buffer, Assay: 50 mM citrate Incubation: 5, Assay: 5 Incubation: 50Β°C, Assay: 50Β°C 0.25% (w/v) CMC (Carboxymethylcellulose sodium) Reducing sugars β€” Incubation: 900 rpm Water-incubated control (in %), activity measured in the presence of organic solvent | Uncertainty about control type

Visualization : Activity + Stability β€” Incubation

One bar per measurement. Colour = solvent, shade = solvent volume.

Structure

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