Serine protease from Engyodontium album BTMFS10

Enzyme Description

Extremophile
No
EC Number

Sequence

Length: 387 amino acids
MRLSILLGLLPLALGAPAVDAVEQRSEPAPLIEARGEMIADKYIVKLKEGSAFASLDATMEKLSGKADHVYKNIFKGFAASLDEKMVEVLRAHPDVEYIEQDAIVNINAEQRNAPWGLARISSTSPGTSSYRYDESAGQGTCVCVIDTGVEASHPEFEGRAQMVKTYYSSSRDGNGHGTHCAGTIGSRTYGVAKKTQIFGVKVLNDQGSSQYSTIISGMDFVANDYRNRNCPNGVVASMSIGGGYSSSVNSAAANLQQSGVMVAVAAGNNNADARNYSPASESSICTVGATDRYDRRSSFSNYGSVLDIFAPGTDIISTWIGGTTRIISGTSMATPHVAGLAAYFMTLGRATASNACRYIAQTANQGDLSGIPFGTVNLLAYNNYQG
Sreeja Chellappan et al. (2010) β€” Characterization of an extracellular alkaline serine protease from marine Engyodontium album BTMFS10
Journal of Industrial Microbiology & Biotechnology  Β· doi:10.1007/s10295-010-0914-3 β†—  Β· Activity + Stability - Incubation
5 measurements
Database ID
UniProt: B2FDP6 β†—
Sequence Annotation
Explicit - Provided
Protein Source
Purified, fungus Engyodontium album BTMFS10

Experimental Data (5 measurements)

5 measurements
Property Assay Solvent Solvent Volume Aqueous Reference Measured Value Units Solution pH Temperature Substrate(s) Product(s) Cofactor(s) Shaking Comments
Activity + Stability - Incubation Activity after incubation (30 minutes at 28Β°C), measured by absorbance spectrophotometry (free tyrosines absorbance measurement, 280 nm) in the presence of organic solvent Isopropanol 10% 100 7 % Incubation: 0.1 M phosphate buffer, Assay: 50 mM phosphate buffer Incubation: 7, Assay: 7 Incubation: 30Β°C, Assay: 30Β°C 0.5% Casein free amino acids , Peptides β€” β€” Non-incubated control (in %), residual activity measured in the presence of organic solvent | High uncertainty about whether residual activity assay was with or without organic solvent
Activity + Stability - Incubation Activity after incubation (30 minutes at 28Β°C), measured by absorbance spectrophotometry (free tyrosines absorbance measurement, 280 nm) in the presence of organic solvent Acetonitrile 10% 100 32 % Incubation: 0.1 M phosphate buffer, Assay: 50 mM phosphate buffer Incubation: 7, Assay: 7 Incubation: 30Β°C, Assay: 30Β°C 0.5% Casein free amino acids , Peptides β€” β€” Non-incubated control (in %), residual activity measured in the presence of organic solvent | High uncertainty about whether residual activity assay was with or without organic solvent
Activity + Stability - Incubation Activity after incubation (30 minutes at 28Β°C), measured by absorbance spectrophotometry (free tyrosines absorbance measurement, 280 nm) in the presence of organic solvent Petroleum Ether 10% 100 >65 % Incubation: 0.1 M phosphate buffer, Assay: 50 mM phosphate buffer Incubation: 7, Assay: 7 Incubation: 30Β°C, Assay: 30Β°C 0.5% Casein free amino acids , Peptides β€” β€” Non-incubated control (in %), residual activity measured in the presence of organic solvent | High uncertainty about whether residual activity assay was with or without organic solvent
Activity + Stability - Incubation Activity after incubation (30 minutes at 28Β°C), measured by absorbance spectrophotometry (free tyrosines absorbance measurement, 280 nm) in the presence of organic solvent Dimethyl Sulfoxide (DMSO) 10% 100 >65 % Incubation: 0.1 M phosphate buffer, Assay: 50 mM phosphate buffer Incubation: 7, Assay: 7 Incubation: 30Β°C, Assay: 30Β°C 0.5% Casein free amino acids , Peptides β€” β€” Non-incubated control (in %), residual activity measured in the presence of organic solvent | High uncertainty about whether residual activity assay was with or without organic solvent
Activity + Stability - Incubation Activity after incubation (30 minutes at 28Β°C), measured by absorbance spectrophotometry (free tyrosines absorbance measurement, 280 nm) in the presence of organic solvent Diethyl Ether 10% 100 >90 % Incubation: 0.1 M phosphate buffer, Assay: 50 mM phosphate buffer Incubation: 7, Assay: 7 Incubation: 30Β°C, Assay: 30Β°C 0.5% Casein free amino acids , Peptides β€” β€” Non-incubated control (in %), residual activity measured in the presence of organic solvent | High uncertainty about whether residual activity assay was with or without organic solvent

Visualization : Activity + Stability β€” Incubation

One bar per measurement. Colour = solvent, shade = solvent volume.

Structure

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