/* OrganiZyme DB - Stylesheet */

html {
    font-size: 17px;
}

:root {
    --primary-dark: #1a2332;
    --primary-blue: #2c4b6d;
    --accent-blue: #4a7ba7;
    --light-gray: #f8f9fa;
    --border-gray: #e1e4e8;
    --text-primary: #2d3748;
    --text-secondary: #5a6c7d;
    --highlight-bg: #f0f4f8;
}

* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

body {
    font-family: 'IBM Plex Sans', -apple-system, BlinkMacSystemFont, sans-serif;
    color: var(--text-primary);
    background-color: #ffffff;
    line-height: 1.6;
}

/* ============================================================
   HEADER & NAV
   ============================================================ */

.header {
    background-color: var(--primary-dark);
    color: white;
    border-bottom: 3px solid var(--accent-blue);
    position: sticky;
    top: 0;
    z-index: 1000;
    box-shadow: 0 2px 8px rgba(0,0,0,0.15);
}

.nav-container {
    max-width: 1400px;
    margin: 0 auto;
    display: flex;
    align-items: center;
    justify-content: space-between;
    padding: 0 2rem;
    height: 70px;
    gap: 2rem;
}

.logo {
    font-family: 'Crimson Pro', serif;
    font-size: 1.8rem;
    font-weight: 700;
    letter-spacing: -0.5px;
    color: white;
    text-decoration: none;
    white-space: nowrap;
    transition: color 0.3s ease;
}

.logo:hover {
    color: var(--accent-blue);
}

.search-bar {
    flex: 0 1 500px;
    position: relative;
}

.search-bar form {
    width: 100%;
}

.search-bar input {
    width: 100%;
    padding: 0.7rem 1rem 0.7rem 2.5rem;
    border: 1px solid rgba(255,255,255,0.2);
    border-radius: 6px;
    background-color: rgba(255,255,255,0.1);
    color: white;
    font-family: 'IBM Plex Sans', sans-serif;
    font-size: 0.95rem;
    transition: all 0.3s ease;
}

.search-bar input::placeholder {
    color: rgba(255,255,255,0.5);
}

.search-bar input:focus {
    outline: none;
    background-color: rgba(255,255,255,0.15);
    border-color: var(--accent-blue);
}

.search-icon {
    position: absolute;
    left: 0.8rem;
    top: 50%;
    transform: translateY(-50%);
    color: rgba(255,255,255,0.6);
    pointer-events: none;
    z-index: 1;
}

.nav-links {
    display: flex;
    gap: 2rem;
    list-style: none;
    white-space: nowrap;
}

.nav-links a {
    color: white;
    text-decoration: none;
    font-size: 0.95rem;
    font-weight: 500;
    letter-spacing: 0.3px;
    transition: color 0.3s ease;
}

.nav-links a:hover {
    color: var(--accent-blue);
}

/* ============================================================
   LAYOUT
   ============================================================ */

.container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 3rem 2rem;
}

/* ============================================================
   SECTIONS
   ============================================================ */

.section {
    background-color: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 2.5rem;
    margin-bottom: 2rem;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
}

.section-title {
    font-family: 'Crimson Pro', serif;
    font-size: 1.8rem;
    font-weight: 700;
    color: var(--primary-dark);
    margin-bottom: 1.5rem;
    padding-bottom: 0.8rem;
    border-bottom: 2px solid var(--accent-blue);
    letter-spacing: -0.3px;
}

.subsection-title {
    font-family: 'Crimson Pro', serif;
    font-size: 1.4rem;
    font-weight: 600;
    color: var(--primary-blue);
    margin-top: 2rem;
    margin-bottom: 1rem;
}

/* ============================================================
   HERO (Home page)
   ============================================================ */

.hero {
    background: linear-gradient(135deg, var(--primary-dark) 0%, var(--primary-blue) 100%);
    border-radius: 8px;
    padding: 4rem 3rem;
    margin-bottom: 2rem;
    color: white;
    text-align: center;
}

.hero h1 {
    font-family: 'Crimson Pro', serif;
    font-size: 3rem;
    font-weight: 700;
    letter-spacing: -0.5px;
    margin-bottom: 0.75rem;
}

.hero p {
    font-size: 1.15rem;
    color: rgba(255,255,255,0.75);
}

/* ============================================================
   STATS GRID
   ============================================================ */

.stats-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(180px, 1fr));
    gap: 1.5rem;
    margin-bottom: 2rem;
}

.stat-card {
    background: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 2rem 1.5rem;
    text-align: center;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
    transition: transform 0.2s ease, box-shadow 0.2s ease;
}

.stat-card:hover {
    transform: translateY(-3px);
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
}

.stat-card h3 {
    font-family: 'Crimson Pro', serif;
    font-size: 2.8rem;
    font-weight: 700;
    color: var(--accent-blue);
    margin-bottom: 0.4rem;
}

.stat-card p {
    color: var(--text-secondary);
    font-size: 0.95rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

/* ============================================================
   SEARCH / FILTER
   ============================================================ */

.search-section {
    background: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 2rem;
    margin-bottom: 2rem;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
}

.search-section h2 {
    font-family: 'Crimson Pro', serif;
    font-size: 1.5rem;
    font-weight: 700;
    color: var(--primary-dark);
    margin-bottom: 1.2rem;
}

.search-input-group {
    display: flex;
    gap: 0.75rem;
}

.search-input-group input,
.search-input-group select {
    padding: 0.7rem 1rem;
    border: 1px solid var(--border-gray);
    border-radius: 6px;
    font-family: 'IBM Plex Sans', sans-serif;
    font-size: 0.95rem;
    color: var(--text-primary);
    background: white;
    transition: border-color 0.2s ease;
}

.search-input-group input {
    flex: 1;
}

.search-input-group input:focus,
.search-input-group select:focus {
    outline: none;
    border-color: var(--accent-blue);
}

.search-input-group select {
    cursor: pointer;
}

.btn-primary {
    padding: 0.7rem 1.8rem;
    background-color: var(--accent-blue);
    color: white;
    border: none;
    border-radius: 6px;
    font-family: 'IBM Plex Sans', sans-serif;
    font-size: 0.95rem;
    font-weight: 600;
    cursor: pointer;
    transition: background-color 0.2s ease;
    white-space: nowrap;
}

.btn-primary:hover {
    background-color: var(--primary-blue);
}

.btn-secondary {
    padding: 0.7rem 1.5rem;
    background-color: var(--light-gray);
    color: var(--text-secondary);
    border: 1px solid var(--border-gray);
    border-radius: 6px;
    font-family: 'IBM Plex Sans', sans-serif;
    font-size: 0.95rem;
    font-weight: 500;
    cursor: pointer;
    text-decoration: none;
    transition: background-color 0.2s ease;
    white-space: nowrap;
}

.btn-secondary:hover {
    background-color: var(--border-gray);
}

/* ============================================================
   INFO GRID (Protein detail)
   ============================================================ */

.info-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(260px, 1fr));
    gap: 1.2rem;
    margin-top: 1.5rem;
}

.info-item {
    background-color: var(--light-gray);
    padding: 1.2rem;
    border-radius: 6px;
    border: 1px solid var(--border-gray);
}

.info-label {
    font-size: 0.8rem;
    font-weight: 600;
    color: var(--text-secondary);
    text-transform: uppercase;
    letter-spacing: 0.5px;
    margin-bottom: 0.5rem;
}

.info-value {
    color: var(--text-primary);
    font-weight: 500;
    font-size: 1rem;
}

.info-value a {
    color: var(--accent-blue);
    text-decoration: none;
}

.info-value a:hover {
    text-decoration: underline;
}

/* ============================================================
   BADGES
   ============================================================ */

.badge {
    display: inline-block;
    padding: 0.25rem 0.75rem;
    border-radius: 20px;
    font-size: 0.85rem;
    font-weight: 600;
}

.badge-extremophile {
    background-color: #fde8d8;
    color: #c05621;
}

.badge-wildtype {
    background-color: #d4edda;
    color: #155724;
}

.badge-mutation {
    background-color: var(--highlight-bg);
    color: var(--primary-blue);
    border: 1px solid var(--border-gray);
}

/* ============================================================
   SEQUENCE
   ============================================================ */

.sequence-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 1rem;
}

.sequence-meta {
    font-size: 0.9rem;
    color: var(--text-secondary);
}

.sequence-display {
    background-color: var(--light-gray);
    border: 1px solid var(--border-gray);
    border-radius: 6px;
    padding: 1.5rem;
    font-family: 'JetBrains Mono', monospace;
    font-size: 0.88rem;
    line-height: 1.8;
    color: var(--text-primary);
    overflow-x: auto;
    white-space: pre-wrap;
    word-break: break-all;
}

.copy-btn {
    background-color: var(--accent-blue);
    color: white;
    border: none;
    padding: 0.45rem 1rem;
    border-radius: 4px;
    cursor: pointer;
    font-family: 'IBM Plex Sans', sans-serif;
    font-size: 0.88rem;
    font-weight: 500;
    transition: background-color 0.2s ease;
}

.copy-btn:hover {
    background-color: var(--primary-blue);
}

/* ============================================================
   MUTATIONS LIST
   ============================================================ */

.mutations-list {
    display: flex;
    flex-wrap: wrap;
    gap: 0.5rem;
    margin-top: 0.5rem;
}

/* ============================================================
   DATA TABLE
   ============================================================ */

.data-table-container {
    overflow-x: auto;
    overflow-y: auto;
    margin-top: 1.5rem;
    max-height: 520px;
    border: 1px solid var(--border-gray);
    border-radius: 6px;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
}

.data-table-container::-webkit-scrollbar {
    width: 8px;
    height: 8px;
}

.data-table-container::-webkit-scrollbar-track {
    background: var(--light-gray);
    border-radius: 4px;
}

.data-table-container::-webkit-scrollbar-thumb {
    background: var(--accent-blue);
    border-radius: 4px;
}

.data-table-container::-webkit-scrollbar-thumb:hover {
    background: var(--primary-blue);
}

.data-table {
    width: 100%;
    border-collapse: collapse;
    background-color: white;
}

.data-table th {
    background-color: var(--primary-dark);
    color: white;
    padding: 0.9rem 1rem;
    text-align: center;
    font-size: 0.8rem;
    font-weight: 600;
    text-transform: uppercase;
    letter-spacing: 0.5px;
    position: sticky;
    top: 0;
    z-index: 10;
    white-space: nowrap;
}

.data-table td {
    padding: 0.85rem 1rem;
    border-bottom: 1px solid var(--border-gray);
    font-size: 0.93rem;
    color: var(--text-primary);
}

.data-table tr:hover {
    background-color: var(--highlight-bg);
}

.data-table a {
    color: var(--accent-blue);
    text-decoration: none;
    font-weight: 500;
}

.data-table a:hover {
    text-decoration: underline;
}

/* ============================================================
   RESULTS CARDS
   ============================================================ */

.results-list {
    display: grid;
    gap: 1rem;
    margin-top: 1.5rem;
}

.result-card {
    background: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 1.5rem;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
    transition: box-shadow 0.2s ease, transform 0.2s ease;
}

.result-card:hover {
    box-shadow: 0 4px 12px rgba(0,0,0,0.1);
    transform: translateY(-2px);
}

.result-card h3 {
    font-family: 'Crimson Pro', serif;
    font-size: 1.3rem;
    font-weight: 700;
    margin-bottom: 0.6rem;
    color: var(--primary-dark);
}

.result-card h3 a {
    color: var(--accent-blue);
    text-decoration: none;
}

.result-card h3 a:hover {
    text-decoration: underline;
}

.result-card p {
    color: var(--text-secondary);
    font-size: 0.93rem;
    margin-bottom: 0.3rem;
}

.result-card p strong {
    color: var(--text-primary);
    font-weight: 600;
}

.result-card code {
    font-family: 'JetBrains Mono', monospace;
    font-size: 0.85rem;
    background: var(--light-gray);
    padding: 0.15rem 0.4rem;
    border-radius: 3px;
    color: var(--primary-blue);
}

/* ============================================================
   ARTICLE REFERENCE BOX
   ============================================================ */

.article-info {
    background-color: var(--highlight-bg);
    padding: 1.5rem;
    border-radius: 6px;
    border-left: 4px solid var(--accent-blue);
}

.article-authors {
    color: var(--text-primary);
    font-weight: 500;
    margin-bottom: 0.4rem;
}

.article-title {
    font-family: 'Crimson Pro', serif;
    font-size: 1.2rem;
    font-weight: 600;
    color: var(--primary-blue);
    margin-bottom: 0.4rem;
}

.article-journal {
    color: var(--text-secondary);
    font-style: italic;
    margin-bottom: 0.4rem;
    font-size: 0.95rem;
}

.article-doi a {
    color: var(--accent-blue);
    text-decoration: none;
    font-size: 0.95rem;
    font-weight: 500;
}

.article-doi a:hover {
    text-decoration: underline;
}

/* ============================================================
   PAGINATION
   ============================================================ */

.pagination {
    display: flex;
    justify-content: center;
    align-items: center;
    gap: 1.5rem;
    margin-top: 2rem;
}

.pagination a {
    color: var(--accent-blue);
    text-decoration: none;
    padding: 0.5rem 1.2rem;
    border: 1px solid var(--accent-blue);
    border-radius: 6px;
    font-size: 0.9rem;
    font-weight: 500;
    transition: all 0.2s ease;
}

.pagination a:hover {
    background-color: var(--accent-blue);
    color: white;
}

.page-info {
    color: var(--text-secondary);
    font-size: 0.9rem;
}

/* ============================================================
   NO RESULTS / EMPTY STATES
   ============================================================ */

.no-results {
    background: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 4rem 3rem;
    text-align: center;
}

.no-results p {
    color: var(--text-secondary);
    font-size: 1.05rem;
    margin-bottom: 0.5rem;
}

.no-results a {
    color: var(--accent-blue);
}

/* ============================================================
   BACK LINK
   ============================================================ */

.back-link {
    margin-top: 2rem;
}

.back-link a {
    color: var(--accent-blue);
    text-decoration: none;
    font-size: 0.95rem;
    font-weight: 500;
    display: inline-flex;
    align-items: center;
    gap: 0.3rem;
    transition: color 0.2s ease;
}

.back-link a:hover {
    color: var(--primary-blue);
}

/* ============================================================
   INFO SECTION (Home about box)
   ============================================================ */

.info-section {
    background: white;
    border: 1px solid var(--border-gray);
    border-radius: 8px;
    padding: 2.5rem;
    margin-bottom: 2rem;
    box-shadow: 0 1px 3px rgba(0,0,0,0.05);
}

.info-section h2 {
    font-family: 'Crimson Pro', serif;
    font-size: 1.6rem;
    font-weight: 700;
    color: var(--primary-dark);
    margin-bottom: 1rem;
    padding-bottom: 0.6rem;
    border-bottom: 2px solid var(--accent-blue);
}

.info-section p {
    color: var(--text-secondary);
    margin-bottom: 0.75rem;
}

.info-section ul {
    margin-left: 1.5rem;
    margin-top: 0.5rem;
}

.info-section li {
    color: var(--text-secondary);
    margin-bottom: 0.4rem;
    font-size: 0.95rem;
}

/* ============================================================
   FOOTER
   ============================================================ */

.footer {
    background-color: var(--primary-dark);
    color: rgba(255,255,255,0.6);
    padding: 0.5rem 0 2rem 0;
    margin-top: 4rem;
    text-align: center;
    font-size: 0.9rem;
    border-top: 3px solid var(--accent-blue);
}

.footer-container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 0 2rem;
}

/* ============================================================
   VISUALIZATION PLACEHOLDER
   ============================================================ */

.viz-placeholder {
    height: 400px;
    background-color: var(--light-gray);
    border: 2px dashed var(--border-gray);
    border-radius: 6px;
    display: flex;
    align-items: center;
    justify-content: center;
    flex-direction: column;
    gap: 0.75rem;
    color: var(--text-secondary);
    margin-top: 1.5rem;
}

.viz-placeholder span {
    font-size: 2.5rem;
}

.viz-placeholder p {
    font-size: 1rem;
    font-weight: 500;
}

/* ============================================================
   ERROR PAGES
   ============================================================ */

.error-code {
    font-family: 'Crimson Pro', serif;
    font-size: 6rem;
    font-weight: 700;
    color: var(--accent-blue);
    line-height: 1;
    margin-bottom: 1rem;
}

/* ============================================================
   RESPONSIVE
   ============================================================ */

@media (max-width: 768px) {
    .nav-container {
        flex-wrap: wrap;
        height: auto;
        padding: 0.75rem 1rem;
        gap: 0.75rem;
    }

    .logo {
        font-size: 1.4rem;
    }

    .nav-links {
        order: 2;
        flex-wrap: wrap;
        gap: 0.75rem 1.2rem;
        width: 100%;
        justify-content: center;
    }

    .nav-links a {
        font-size: 0.88rem;
    }

    .search-bar {
        order: 3;
        flex: 1 1 100%;
    }

    .search-input-group {
        flex-direction: column;
    }

    .container {
        padding: 1.5rem 1rem;
    }

    .section {
        padding: 1.5rem 1rem;
    }

    .section-title {
        font-size: 1.4rem;
    }

    .stats-grid {
        grid-template-columns: repeat(2, 1fr);
        gap: 0.75rem;
    }

    .hero h1 {
        font-size: 1.8rem;
    }

    .hero p {
        font-size: 1rem;
    }

    .data-table {
        font-size: 0.82rem;
    }

    .data-table th,
    .data-table td {
        padding: 0.5rem 0.6rem;
    }

    .info-grid {
        grid-template-columns: 1fr;
    }

    .footer-logos {
        flex-direction: column;
        align-items: center;
        gap: 1.5rem;
    }

    .footer-logos-left,
    .footer-logos-right {
        width: 100%;
        align-items: center;
    }

    .footer-center-text {
        order: -1;
        width: 100%;
    }

    .btn-primary,
    .btn-secondary {
        width: 100%;
        text-align: center;
        padding: 0.75rem 1rem;
    }
}

/* ── Tablet ── */
@media (max-width: 1024px) and (min-width: 769px) {
    .nav-container {
        padding: 0 1.5rem;
        gap: 1rem;
    }

    .search-bar {
        flex: 0 1 320px;
    }

    .nav-links {
        gap: 1.2rem;
    }

    .nav-links a {
        font-size: 0.9rem;
    }

    .container {
        padding: 2rem 1.5rem;
    }

    .stats-grid {
        grid-template-columns: repeat(3, 1fr);
    }
}

/* ── Footer logos ── */
.footer-logos {
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 2rem;
    flex-wrap: wrap;
    width: 100%;
}
.footer-logos-left,
.footer-logos-right {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 0.75rem;
}
.footer-center-text {
    text-align: center;
    flex: 1;
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
}
.footer-group-label {
    font-size: 0.82rem;
    font-weight: 600;
    letter-spacing: 0.12em;
    text-transform: uppercase;
    color: rgba(255,255,255,1.0);
    margin: 0;
}
.footer-logo {
    height: 110px;
    width: auto;
    opacity: 0.93;
    transition: opacity 0.2s ease;
}
.footer-logo:hover { opacity: 1; }
.footer-logo-link { display:inline-flex; }

/* ============================================================
   STRUCTURE VIEWER (protein detail)
   ============================================================ */

#viz-toolbar {
    background: var(--viz-toolbar-bg);
    border: 1px solid var(--viz-toolbar-border);
    border-bottom: none;
    border-radius: 6px 6px 0 0;
    padding: 0.6rem 0.75rem;
}
.viz-row { display:flex; align-items:center; flex-wrap:wrap; gap:0.5rem; }
.viz-group { display:flex; align-items:center; gap:0.45rem; }
.viz-label {
    font-size:0.75rem; font-weight:600; letter-spacing:0.4px;
    text-transform:uppercase; color:var(--viz-label-color);
    white-space:nowrap; min-width:3.5rem;
}
.viz-btn-group { display:flex; gap:0.3rem; flex-wrap:wrap; }

.viz-btn {
    padding:0.28rem 0.65rem; font-size:0.79rem;
    font-family:'IBM Plex Mono','JetBrains Mono',monospace; font-weight:500;
    border:1px solid var(--viz-btn-border); border-radius:3px;
    background:var(--viz-btn-bg); color:var(--viz-btn-color);
    cursor:pointer; transition:background 0.12s, color 0.12s, border-color 0.12s;
    white-space:nowrap;
}
.viz-btn:hover { background:var(--viz-btn-hover-bg); color:var(--viz-btn-hover-color); border-color:var(--viz-btn-hover-border); }
.viz-btn.viz-btn-active { background:var(--viz-active-bg); color:var(--viz-active-color); border-color:var(--viz-active-border); font-weight:700; }

.viz-bg-toggle {
    width:2rem; height:2rem; border-radius:50%;
    border:1px solid var(--viz-btn-border); background:var(--viz-btn-bg);
    color:var(--viz-btn-color); cursor:pointer; font-size:1rem;
    display:flex; align-items:center; justify-content:center;
    transition:background 0.12s, transform 0.15s;
}
.viz-bg-toggle:hover { transform:scale(1.1); background:var(--viz-btn-hover-bg); }

.viz-download {
    padding:0.28rem 0.65rem; font-size:0.79rem;
    font-family:'IBM Plex Mono','JetBrains Mono',monospace; font-weight:600;
    border:1px solid var(--viz-btn-border); border-radius:3px;
    background:var(--viz-btn-bg); color:var(--viz-btn-color);
    text-decoration:none; transition:background 0.12s; white-space:nowrap;
}
.viz-download:hover { background:var(--viz-btn-hover-bg); color:var(--viz-btn-hover-color); }

#structure-viewer {
    width:100%; height:520px;
    border:1px solid var(--viz-toolbar-border);
    border-radius:0 0 6px 6px; overflow:hidden; position:relative;
}
#viewer-loading {
    position:absolute; inset:0; display:flex;
    align-items:center; justify-content:center;
    font-size:0.9rem; color:var(--viz-loading-color);
    letter-spacing:0.3px; pointer-events:none;
}

/* Night mode (default) */
#viz-toolbar, #structure-viewer {
    --viz-toolbar-bg:     #1c1f26;
    --viz-toolbar-border: #383d48;
    --viz-label-color:    #7a8394;
    --viz-btn-bg:         #252930;
    --viz-btn-border:     #3e4453;
    --viz-btn-color:      #c8cdd8;
    --viz-btn-hover-bg:   #2f3542;
    --viz-btn-hover-color:#e8ecf4;
    --viz-btn-hover-border:#5a6070;
    --viz-active-bg:      #3a7bd5;
    --viz-active-color:   #ffffff;
    --viz-active-border:  #2e6bbf;
    --viz-loading-color:  rgba(200,210,220,0.5);
}

/* Day mode */
#viz-toolbar.day-mode, #structure-viewer.day-mode {
    --viz-toolbar-bg:     #f0f2f5;
    --viz-toolbar-border: #c8cdd6;
    --viz-label-color:    #5a6070;
    --viz-btn-bg:         #ffffff;
    --viz-btn-border:     #c0c6d0;
    --viz-btn-color:      #2a2e38;
    --viz-btn-hover-bg:   #e4e8f0;
    --viz-btn-hover-color:#111318;
    --viz-btn-hover-border:#8090a8;
    --viz-active-bg:      #2563eb;
    --viz-active-color:   #ffffff;
    --viz-active-border:  #1d55d0;
    --viz-loading-color:  rgba(60,70,90,0.55);
}

/* ============================================================
   COMPOUND / SOLVENT MODAL
   ============================================================ */

.compound-link { color:var(--accent-blue); cursor:pointer; text-decoration:underline; font-weight:500; }
.compound-link:hover { color:var(--primary-blue); }

.modal { display:none; position:fixed; z-index:2000; left:0; top:0; width:100%; height:100%;
         background:rgba(0,0,0,0.5); animation:fadeIn 0.2s ease; }
.modal.active { display:flex; align-items:center; justify-content:center; }
.modal-content { background:white; border-radius:8px; width:90%; max-width:640px;
                 max-height:85vh; overflow-y:auto; box-shadow:0 4px 24px rgba(0,0,0,0.2);
                 animation:slideUp 0.25s ease; }
.modal-header { display:flex; justify-content:space-between; align-items:center;
                padding:1.5rem 2rem; border-bottom:2px solid var(--accent-blue);
                background:var(--highlight-bg); }
.modal-title { font-family:'Crimson Pro',serif; font-size:1.6rem; font-weight:700;
               color:var(--primary-dark); margin:0; }
.modal-close { background:none; border:none; font-size:1.8rem; color:var(--text-secondary);
               cursor:pointer; line-height:1; transition:color 0.2s; }
.modal-close:hover { color:var(--primary-dark); }
.modal-body { padding:2rem; }
.compound-info-grid { display:grid; grid-template-columns:1fr 1fr; gap:1rem; margin-bottom:1.5rem; }
.compound-info-item { background:var(--light-gray); padding:1rem; border-radius:6px; border:1px solid var(--border-gray); }
.compound-info-label { font-size:0.8rem; font-weight:600; color:var(--text-secondary);
                       text-transform:uppercase; letter-spacing:0.5px; margin-bottom:0.4rem; }
.compound-info-value { color:var(--text-primary); font-weight:500; }
.compound-info-value a { color:var(--accent-blue); text-decoration:none; }
.compound-info-value a:hover { text-decoration:underline; }
.structure-container { background:white; border:1px solid var(--border-gray);
                       border-radius:6px; padding:1.2rem; text-align:center; }
.structure-label { font-size:0.8rem; font-weight:600; color:var(--text-secondary);
                   text-transform:uppercase; letter-spacing:0.5px; margin-bottom:1rem; }
#structure-render svg { max-width:100%; height:auto; }

/* ============================================================
   EXTREMOPHILE BADGES
   ============================================================ */

.badge.yes { background-color:#d4edda; color:#155724; display:inline-block;
             padding:0.3rem 0.8rem; border-radius:20px; font-size:0.9rem; font-weight:600; }
.badge.no  { background-color:#f8d7da; color:#721c24; display:inline-block;
             padding:0.3rem 0.8rem; border-radius:20px; font-size:0.9rem; font-weight:600; }

/* ============================================================
   PAGINATION BAR (shared by protein.html and measurements.html)
   ============================================================ */

.pagination-bar { display:flex; align-items:center; flex-wrap:wrap; gap:0.75rem;
                  margin-top:1.8rem; padding-top:1.2rem; border-top:1px solid var(--border-gray); }
.pagination-nav { display:flex; gap:0.3rem; }
.pagination-pages { display:flex; gap:0.3rem; align-items:center; }
.page-btn { display:inline-block; padding:0.35rem 0.75rem;
            border:1px solid var(--border-gray); border-radius:4px;
            font-size:0.88rem; color:var(--accent-blue); text-decoration:none;
            transition:all 0.15s ease; white-space:nowrap; }
.page-btn:hover { background:var(--accent-blue); color:white; border-color:var(--accent-blue); }
.page-btn.current { background:var(--primary-dark); color:white; border-color:var(--primary-dark);
                    font-weight:600; pointer-events:none; }
.page-btn.disabled { color:var(--border-gray); border-color:var(--border-gray); pointer-events:none; }
.page-ellipsis { padding:0.35rem 0.3rem; color:var(--text-secondary); font-size:0.88rem; }

@keyframes fadeIn  { from{opacity:0;} to{opacity:1;} }
@keyframes slideUp { from{transform:translateY(40px);opacity:0;} to{transform:translateY(0);opacity:1;} }

/* ============================================================
   MOL* — hide built-in UI chrome, our toolbar is the sole control
   ============================================================ */
#structure-viewer .msp-plugin-content,
#structure-viewer .msp-layout-region,
#structure-viewer .msp-sequence,
#structure-viewer .msp-controls-section { display: none !important; }
#structure-viewer canvas { border-radius: 0 0 6px 6px; }